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Gentle zap during thyroid surgery may save Patients' voices

NCT ID NCT07706699

Disease control Sponsor: The Second Affiliated Hospital of Kunming Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests whether using a low electrical current (3 or 5 milliamps) during thyroid surgery helps surgeons locate and avoid damaging the nerve that controls the voice box. About 150 adults having their first thyroid surgery will be randomly assigned to one of two current levels. The main goal is to see if this technique reduces the number of patients with permanent voice loss six months after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
low-current electrical stimulation (3 mA or 5 mA) used during surgery to help identify the nerve that controls the voice box
What this could lead to
If effective, this simple technique could become a standard step in thyroid surgery to lower the risk of permanent voice damage.
What could go wrong
This is a single-center study with 150 participants, so results may not apply broadly. The stimulation itself is low-risk, but the main risk is that it may not reduce nerve injury compared to standard methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

150 people

The number who actually took part.

Started

Jun 2024

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients scheduled for thyroid surgery. * No history of prior thyroid or neck surgery. * Normal bilateral vocal cord mobility on preoperative electronic laryngoscopy. * Written informed consent provided before enrollment. Exclusion Criteria: * Preoperative recurrent laryngeal nerve dysfunction. * Previous neck surgery. * Incomplete clinical data. * Severe comorbidities precluding standardized perioperative assessment.

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Conditions

The condition(s) this trial relates to.

Recurrent Laryngeal Nerve Injuries thyroid gland disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Recurrent laryngeal nerve injury Thyroid disease

Contacts and locations

Locations

  • The Second Affiliated Hospital of Kunming Medical University

    Kunming, Yunnan, 650000, China

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