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Customizing electrical current during thyroid surgery could protect vocal cord nerves

NCT ID NCT07710365

Knowledge-focused Sponsor: Medical University of Gdansk Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study investigates whether using a personalized electrical current to monitor the nerve that controls the vocal cords during thyroid surgery is as effective as the standard fixed current. Researchers will analyze data from over 600 patients to see if individualizing the stimulation reduces unnecessary nerve stress while still providing reliable monitoring. The goal is to improve surgical safety by tailoring the monitoring to each patient.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to safer thyroid surgery by reducing the risk of nerve damage.
What could go wrong
This is an observational study, so it does not test a new treatment. The findings may not change current practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

623 people

The number who actually took part.

Started

Jun 2020

Finished

Feb 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of consecutive adult patients who underwent thyroid surgery with continuous intraoperative neuromonitoring (C-IONM) at the Department of Endocrine and General Surgery, Medical University of Gdańsk, Poland, between June 2020 and July 2024. Patients were identified retrospectively from the institutional thyroid surgery database and neuromonitoring records. Clinical and operative data were collected as part of routine clinical care. Participants were included consecutively during the study period.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. * Patients undergoing thyroid surgery with continuous intraoperative neuromonitoring (C-IONM) of the vagus nerve. * Availability of complete intraoperative neuromonitoring recordings suitable for analysis. * Availability of complete clinical and operative data. Exclusion Criteria: * Age younger than 18 years. * Incomplete or technically inadequate neuromonitoring recordings. * Loss of signal or recurrent laryngeal nerve palsy preventing reliable amplitude analysis. * Missing or incomplete clinical data required for the study.

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Conditions

The condition(s) this trial relates to.

thyroid gland disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Thyroid disease

Contacts and locations

Locations

  • The University Clinical Centre in Gdansk

    Gdansk, 80-135, Poland

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