Could your nerves predict liver cancer? new study investigates

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Group A: * Over 18 years of age * Affiliated with a social security system * Sufficient command of the French language to hold a conversation and read * Signature of an informed consent form * Compensated cirrhosis classified as CHILD-Pugh A with clinical indication for liver biopsy (either for the etiological diagnosis or confirmation of cirrhosis, or for the etiological diagnosis of liver damage) * Liver biopsy scheduled as part of routine care for a diagnosis of cirrhosis without HCC Group B: * Over 18 years of age * Affiliated with a social security system * Sufficient command of the French language to hold a conversation and read * Signature of an informed consent form * Compensated cirrhosis classified as CHILD-Pugh A with clinical indication for liver biopsy (either for the etiological diagnosis of cirrhosis or its confirmation; or for the etiological diagnosis of liver damage) * Liver biopsy scheduled as part of routine care for the diagnosis of suspected HCC (based on standard imaging criteria) Exclusion Criteria: * Personal history of cancer in the broad sense (including HCC prior to inclusion in the study) * Pregnant or breastfeeding women * Adults subject to legal protection measures (guardianship, curatorship) * Contraindications to trans-parietal liver biopsy: clinical or radiological ascites, coagulation disorders, curative anticoagulation that cannot be suspended, dilation of the bile ducts * Persons deprived of their liberty by judicial or administrative decision * Wearers of electronic implants (pacemakers, implantable cardioverter defibrillators, cochlear implants, brain implants, etc.) * Psychotic disorders * Degenerative neurological disorders (Parkinson's disease and related disorders, dementia, Korsakoff's syndrome, etc.) * Antiarrhythmic treatment: * Class Ia: Disopyramide and Quinidine * Class Ic: Flecainide and Propafenone * Neuroleptic psychotropic treatment affecting the ANS (haloperidol, chlorpromazine, olanzapine, clozapine, quetiapine), tricyclic antidepressants (e.g., amitriptyline, amoxapine, clomipramine, etc.)