Psoriasis 'Memory' targeted in new skin study

NCT ID NCT05185258

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether combining a medicated foam (Enstilar) with ultraviolet light therapy can change immune cells in psoriasis skin that may 'remember' the disease and cause it to return. Researchers will take skin samples from 12 adults with stable plaque psoriasis before, during, and after treatment to track these cells. The goal is to understand why psoriasis comes back even after skin looks healed, not to test a new cure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Enstilar foam and narrow-band ultraviolet B (NB-UVB) light therapy

What this could lead to

If successful, this could reveal how to prevent psoriasis from coming back after treatment, pointing toward longer-lasting remission.

What could go wrong

This is a very small, early-phase study with only 12 participants, so results may not apply to everyone. It focuses on skin cell changes, not on curing the disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

erythematosquamous dermatosis psoriasis Skin and Connective Tissue Diseases Skin Diseases, Papulosquamous skin disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Dermatology

    Aarhus N, Central Jutland, 8200, Denmark