Psoriasis 'Memory' targeted in new skin study
NCT ID NCT05185258
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether combining a medicated foam (Enstilar) with ultraviolet light therapy can change immune cells in psoriasis skin that may 'remember' the disease and cause it to return. Researchers will take skin samples from 12 adults with stable plaque psoriasis before, during, and after treatment to track these cells. The goal is to understand why psoriasis comes back even after skin looks healed, not to test a new cure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Enstilar foam and narrow-band ultraviolet B (NB-UVB) light therapy
- What this could lead to
- If successful, this could reveal how to prevent psoriasis from coming back after treatment, pointing toward longer-lasting remission.
- What could go wrong
- This is a very small, early-phase study with only 12 participants, so results may not apply to everyone. It focuses on skin cell changes, not on curing the disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Dermatology
Aarhus N, Central Jutland, 8200, Denmark
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