New scan may spare men from unnecessary prostate biopsies
NCT ID NCT05154162
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a PSMA PET scan helps doctors better diagnose significant prostate cancer in men whose MRI results are unclear or negative. About 660 men with no prior prostate cancer or biopsy will be randomly assigned to receive either standard care or an additional PSMA PET scan. If the PSMA PET is negative, those men may avoid a biopsy, potentially reducing unnecessary procedures and their risks.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Austin Health
Melbourne, Victoria, 3084, Australia
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Cabrini Health
Melbourne, Victoria, 3144, Australia
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Peter MacCallum Cancer Centre
Melbourne, Victoria, 3000, Australia
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Royal Adelaide Hospital
Adelaide, South Australia, 5000, Australia
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Royal Brisbane and Women's Hospital
Brisbane, Queensland, 4006, Australia
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St Vincent's Hospital
Sydney, New South Wales, 2010, Australia
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Other studies related to the condition(s) this trial covers.
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