New imaging test may predict which breast cancer patients respond to hormone therapy
NCT ID NCT04573231
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study is testing whether a special PET/CT scan that looks for a protein called PSMA can help predict resistance to anti-androgen therapy in people with a specific type of metastatic breast cancer (HER2-negative, AR-positive). About 13 participants will receive an injection of a radioactive tracer and undergo imaging. The goal is to see if PSMA levels in tumors are linked to treatment resistance, which could help select patients for future therapies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 18F-DCFPyL (a radioactive tracer for PET/CT imaging)
- What this could lead to
- If successful, this could help identify which patients with this type of breast cancer might benefit from anti-androgen treatments, leading to more personalized therapy.
- What could go wrong
- This is a very small early-phase study (13 people) focused on imaging, not treatment. It may not lead to any change in patient care or outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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University of Wisconsin School of Medicine and Public Health
RECRUITINGMadison, Wisconsin, 53705, United States
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