Magic mushroom compound tested for Tough-to-Treat OCD
NCT ID NCT04882839
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a drug called psilocybin, given alongside talk therapy, can help people with severe obsessive-compulsive disorder (OCD) who haven't gotten better with standard treatments. Fifteen adults will receive three eight-hour sessions under the influence of psilocybin, plus 12 therapy sessions. Researchers will measure changes in OCD symptoms, anxiety, and depression to see if the approach is safe and effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
psilocybin
What this could lead to
If it works, this could point toward a new treatment option for people with severe OCD who haven't been helped by standard therapies.
What could go wrong
This is a very small early-phase trial with only 15 people, so results may not apply to everyone. Psilocybin can cause intense psychological experiences and side effects.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OBSESSIVE - COMPULSIVE DISORDER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Beer Sheva Mental Health Center
RECRUITINGBeersheba, 8461144, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact