Magic mushrooms tested for depression in veterans with spinal injuries
NCT ID NCT07251491
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether psilocybin (the active ingredient in magic mushrooms) is safe and tolerable for veterans with spinal cord injury who also have depression. Thirty participants will receive low, medium, or high doses and be monitored for side effects like pain, muscle spasms, and blood pressure changes. The study also tracks how well the psychedelic experience is tolerated and any changes in depression symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Psilocybin (magic mushrooms)
What this could lead to
If it works, this could point toward a new treatment option for depression in people with spinal cord injury.
What could go wrong
This is an early-phase trial with only 30 participants, so results may not apply broadly. Psilocybin can cause intense psychological effects and temporary increases in blood pressure or anxiety.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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James J. Peters Department of Veterans Affairs Medical Center
RECRUITINGThe Bronx, New York, 10468, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••