Magic mushroom compound tested for back pain and depression
NCT ID NCT06355414
First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This study looks at how psilocybin (the active ingredient in magic mushrooms) affects mood and pain in people with both chronic low back pain and depression. About 40 adults will receive either a single high dose of psilocybin or a control drug. Researchers will track changes in positive and negative emotions, pain-related thoughts, and pain sensitivity over one month.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Johns Hopkins University School of Medicine
RECRUITINGBaltimore, Maryland, 21224, United States
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