Brain scans reveal Psilocybin's effect on opioid addiction circuits

NCT ID NCT06810310

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 35 times

Summary

This study looks at how psilocybin (a psychedelic drug) changes brain activity related to motivation and self-control in people with opioid use disorder. Twenty-four adults will receive either a low or high dose of psilocybin and have their brains scanned with fMRI before and after. The goal is to understand how psilocybin might affect brain circuits linked to drug cravings and relapse.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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