Magic mushroom compound probed as brain tool against opioid addiction

This study looks at how psilocybin, the active ingredient in magic mushrooms, affects brain circuits linked to motivation and self-control in people with opioid use disorder. Twenty-four adults in the Philadelphia area will receive either a low or high dose of psilocybin, then undergo brain scans and behavioral tests. The goal is to understand brain changes that might help prevent relapse, not to test psilocybin as a direct treatment.