Can a blood injection stop hernias from returning?
NCT ID NCT05023174
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether injecting platelet-rich plasma (PRP) during hiatal hernia repair can lower the chance of the hernia coming back. About 150 adults with large hiatal hernias will be randomly assigned to get either standard surgery with mesh or surgery plus PRP. The main goal is to see if PRP reduces hernia recurrence one year after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
platelet-rich plasma (PRP)
What this could lead to
If it works, this could reduce the chance of a hiatal hernia coming back after surgery, improving long-term outcomes for people with GERD.
What could go wrong
This is a small pilot study, so results may not be definitive. PRP is generally safe, but its effectiveness for this use is unproven, and the trial is not yet complete.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hoag Hospital
Newport Beach, California, 92663, United States
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Keck Hospital of USC
Los Angeles, California, 90033, United States