Which surgery keeps hiatal hernias away longer? study aims to find out

NCT ID NCT04695171

Terminated Knowledge-focused Sponsor: Foregut Research Foundation Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This registry tracked 336 adults who had surgery for a large hiatal hernia (over 3 cm) at least two years earlier. Some received a LINX magnetic implant to strengthen the valve between the stomach and esophagus, while others had a fundoplication (wrapping the stomach around the esophagus). The goal was to see which method better prevents the hernia from coming back. However, the study was terminated early, so the full picture is unclear.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LINX Reflux Management System (magnetic bead implant) or fundoplication surgery
What this could lead to: If successful, this could help doctors choose the best surgical option to prevent hiatal hernias from coming back after repair.
What could go wrong: The study was terminated early, so results may be incomplete. It only looks back at past surgeries, not a controlled experiment, so findings are less reliable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease hiatus hernia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTRO ESOPHAGEAL REFLUX HIATAL HERNIA HIATAL HERNIA LARGE HIATAL HERNIA, PARAESOPHAGEAL REFLUX ACID REFLUX, GASTROESOPHAGEAL

Contacts and locations

Locations

East Carolina University

Greenville, North Carolina, 27858, United States
Esophageal Institute

Pittsburgh, Pennsylvania, 15224, United States
Institute of Esophageal and Reflux Surgery

Lone Tree, Colorado, 80124, United States
Keck Medical Center of USC

Los Angeles, California, 90033, United States
South Florida Reflux Center

Coral Springs, Florida, 33065, United States
University of Texas

Austin, Texas, 78712, United States

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