New study: can proton therapy spare women from bowel problems after cancer surgery?

NCT ID NCT04567771

First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times

Summary

This study compares two types of radiation therapy—proton therapy and standard intensity-modulated radiation therapy (IMRT)—given after surgery for cervical or endometrial cancer. The goal is to see if proton therapy causes fewer bowel side effects. About 120 women will fill out quality-of-life questionnaires and have their side effects tracked. The results could help doctors choose the gentler treatment option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Radiation therapy (proton or intensity-modulated)
What this could lead to
If proton therapy causes fewer bowel side effects than standard IMRT, it could become a gentler option for women after surgery for cervical or endometrial cancer.
What could go wrong
This is a small early-phase study (120 people) comparing side effects, not testing a cure. Results may not show a clear benefit, and individual experiences vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

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