New study: can proton therapy spare women from bowel problems after cancer surgery?
NCT ID NCT04567771
First seen Nov 15, 2025 · Last updated Jun 23, 2026 · Updated 28 times
Summary
This study compares two types of radiation therapy—proton therapy and standard intensity-modulated radiation therapy (IMRT)—given after surgery for cervical or endometrial cancer. The goal is to see if proton therapy causes fewer bowel side effects. About 120 women will fill out quality-of-life questionnaires and have their side effects tracked. The results could help doctors choose the gentler treatment option.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
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Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Radiation therapy (proton or intensity-modulated)
What this could lead to
If proton therapy causes fewer bowel side effects than standard IMRT, it could become a gentler option for women after surgery for cervical or endometrial cancer.
What could go wrong
This is a small early-phase study (120 people) comparing side effects, not testing a cure. Results may not show a clear benefit, and individual experiences vary.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.