Proton beam may spare heart and lungs in breast cancer radiation

NCT ID NCT03270072

Ongoing Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at 100 women with stage II or III breast cancer to see if proton beam radiation causes less damage to the heart and lungs than standard X-ray radiation. Participants receive either type of radiation as part of a larger trial. Researchers will measure changes in heart function and lung tissue using imaging and scans. The goal is to find out which radiation method is safer for nearby organs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: proton beam radiation
What this could lead to: If successful, this could show that proton beam radiation causes less heart and lung damage than conventional radiation for breast cancer patients.
What could go wrong: This is an observational study, not a treatment trial. It only measures side effects, not whether one radiation type cures cancer better. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER STAGE II BREAST CANCER STAGE III

Contacts and locations

Locations

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.