Proton beam aims to zap prostate cancer return with fewer side effects

NCT ID NCT00969111

Recruiting now Disease control Sponsor: Proton Collaborative Group Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests proton radiation therapy for men with prostate cancer that has returned or is at risk of returning after prostate removal surgery. Researchers want to see if this precise type of radiation can control the cancer while causing fewer side effects than standard radiation. About 70 men will receive different doses of proton therapy depending on their risk level.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: proton radiation therapy
What this could lead to: If successful, this could offer a more precise radiation option for prostate cancer patients after surgery, potentially reducing side effects while controlling the disease.
What could go wrong: This is a small, early-phase study with only 70 participants, so results may not apply to everyone. Side effects like bowel or bladder issues are still possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

Inova Schar Cancer Institute
RECRUITING

Fairfax, Virginia, 22031, United States
McLaren Proton Therapy Center
RECRUITING

Flint, Michigan, 48532, United States
Mercy David C. Pratt Cancer Center
RECRUITING

St Louis, Missouri, 63141, United States
Northwestern Medicine Chicago Proton Center
RECRUITING

Warrenville, Illinois, 60555, United States
Proton Center of Arkansas
RECRUITING

Little Rock, Arkansas, 72205, United States
University of Florida Proton Therapy Institute
RECRUITING

Jacksonville, Florida, 32206, United States

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