Brain shield during heart valve procedure? PROTEMBO trial results
NCT ID NCT05873816
First seen Jan 11, 2026 · Last updated May 14, 2026 · Updated 13 times
Summary
This study tested a new device (ProtEmbo) designed to catch debris and protect the brain during a minimally invasive heart valve replacement (TAVR) for people with severe aortic stenosis. 284 participants were randomly assigned to receive the ProtEmbo device, no protection, or a different device. The researchers measured major heart and brain complications at 30 days and new brain lesions on MRI.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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BayCare Health System / Morton Plant Hospital
Clearwater, Florida, 33756, United States
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Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
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Columbia University Medical Center / NYPH
New York, New York, 10032, United States
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Dresden Herzzentrum
Dresden, 01307, Germany
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Gdansk Uniwersyteckie Centrum Kliniczne
Gdansk, 80-214, Poland
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Lübeck Universitätsklinikum Schleswig-Holstein Campus
Lübeck, 23562, Germany
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Morristown Medical Center
Morristown, New Jersey, 07690, United States
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Mount Sinai Hospital
New York, New York, 10029, United States
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NYU Langone
New York, New York, 10016, United States
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Saint Luke's Hospital of Kansas City
Kansas City, Missouri, 64111, United States
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State University of New York at Buffalo
Buffalo, New York, 14203, United States
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Trier Krankenhaus der Barmherzigen Brüder
Trier, 54292, Germany
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Tucson Medical Center Health
Tucson, Arizona, 85712, United States
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Ulm Universitätsklinikum
Ulm, 89081, Germany
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of Texas, Memorial Hermann Hospital
Houston, Texas, 77030, United States
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University of Virginia, Charlottesville
Charlottesville, Virginia, 22908, United States
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Washington University - St. Louis
St Louis, Missouri, 63110, United States
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Weill Medical College / Cornell University
New York, New York, 10065, United States
Conditions
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