Can tighter blood pressure control shield hearts during breast cancer therapy?

NCT ID NCT06023576

Recruiting now Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a more aggressive approach to managing high blood pressure during breast cancer treatment can safely reduce the risk of heart damage. About 130 women with breast cancer who are receiving anthracycline chemotherapy will be randomly assigned to either intensive or standard blood pressure goals. The main goal is to see if intensive control lowers blood pressure more effectively over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: antihypertensive medications (ACE inhibitors, ARBs, beta-blockers, diuretics, etc.)
What this could lead to: If successful, this could show that aggressively managing blood pressure during breast cancer treatment lowers the risk of heart damage, leading to better long-term heart health for cancer patients.
What could go wrong: This is a small, early-phase trial (130 participants) testing a treatment strategy, not a new drug. The intensive approach may not prove more effective than standard care, and side effects from stronger blood pressure lowering are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Cardiotoxicity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER CARDIOTOXICITY

Contacts and locations

Locations

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
RECRUITING

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
RECRUITING

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
RECRUITING

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
RECRUITING

Rockville Centre, New York, 11553, United States
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)
RECRUITING

Commack, New York, 11725, United States
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
RECRUITING

Harrison, New York, 10604, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.