Could a traditional chinese medicine compound boost prostate cancer treatment?
NCT ID NCT07163910
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tests whether adding homoharringtonine (a drug from a Chinese evergreen plant) to standard hormone therapy before prostate removal can improve outcomes for men with high-risk or advanced prostate cancer. About 93 participants will receive the drug combination before surgery, and researchers will measure how many achieve a complete or major response. The goal is to find a more effective neoadjuvant treatment for this aggressive cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- homoharringtonine (a plant-derived chemotherapy drug) combined with androgen deprivation therapy (hormone therapy)
- What this could lead to
- If successful, this combination could become a new pre-surgery treatment option to improve outcomes for men with advanced or high-risk prostate cancer.
- What could go wrong
- This is a small, early-phase trial (Phase 2) with no control group, so results may not prove effectiveness. The drug can cause side effects like bone marrow suppression and heart rhythm issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Zhongda Hospital
RECRUITINGNanjing, Jiangsu, 210009, China
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