Could a traditional chinese medicine compound boost prostate cancer treatment?

NCT ID NCT07163910

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests whether adding homoharringtonine (a drug from a Chinese evergreen plant) to standard hormone therapy before prostate removal can improve outcomes for men with high-risk or advanced prostate cancer. About 93 participants will receive the drug combination before surgery, and researchers will measure how many achieve a complete or major response. The goal is to find a more effective neoadjuvant treatment for this aggressive cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

homoharringtonine (a plant-derived chemotherapy drug) combined with androgen deprivation therapy (hormone therapy)

What this could lead to

If successful, this combination could become a new pre-surgery treatment option to improve outcomes for men with advanced or high-risk prostate cancer.

What could go wrong

This is a small, early-phase trial (Phase 2) with no control group, so results may not prove effectiveness. The drug can cause side effects like bone marrow suppression and heart rhythm issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhongda Hospital

    RECRUITING

    Nanjing, Jiangsu, 210009, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••