New study tracks brain and energy side effects of prostate cancer meds

NCT ID NCT07181122

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 102 men with metastatic hormone-sensitive prostate cancer who are taking standard drugs (abiraterone, apalutamide, enzalutamide, or darolutamide) plus hormone therapy. Researchers will check thinking skills, fatigue, mood, and sleep at the start, 3 months, and 6 months using simple questionnaires. The goal is to see how these treatments affect daily life and mental function in the real world.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Androgen receptor pathway inhibitors (abiraterone, apalutamide, enzalutamide, darolutamide)

What this could lead to

If successful, this study could help doctors understand how these drugs affect thinking, energy, and mood, leading to better support for patients.

What could go wrong

This is an observational study, not a treatment trial. It only measures outcomes without testing a new therapy, so it won't directly improve treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression Fatigue insomnia metastatic prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Etlik City Hospital Medical Oncology Department

    RECRUITING

    Ankara, Yenimahalle, 06270, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Gazi University Medical Oncology Department

    RECRUITING

    Ankara, Çankaya, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••