Could a diabetes drug boost radiation to fight returning prostate cancer?
NCT ID NCT04536805
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is for men whose prostate cancer has returned in the same area after they already had radiation and surgery. The researchers want to see if giving a very precise, high-dose radiation treatment (called SBRT) along with the diabetes drug metformin can safely control the cancer again. About 44 participants will receive different radiation doses to find the best one. The study will track PSA levels for up to 5 years to see how well the treatment works.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHRU de BREST - HOPITAL MORVAN
Brest, 29200, France
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Centre Eugene Marquis
Rennes, 35042, France
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Centre GEORGES FRANCOIS LECLERC
Dijon, 21079, France
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Centre Henri Becquerel
Rouen, 76038, France
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Centre LEON BERARD
Lyon, 69373, France
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Centre OSCAR LAMBRET
Lille, 59020, France
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Chru Bretonneau
Tours, 37044, France
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Clinique Victor Hugo
Le Mans, 72100, France
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ICANS - Institut de cancérologie Strasbourg Europe
Strasbourg, 67200, France
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Institut de Cancerologie de L'Ouest
Angers, 49055, France
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Institut de Cancerologie de L'Ouest
Saint-Herblain, 44805, France
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Societe de Recherche Oncologique Clinique 37 (Roc 37)
Chambray-lès-Tours, 37170, France