Could two radiation sessions be as good as five for prostate cancer?

NCT ID NCT05600400

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This trial compares two different schedules of MRI-guided radiation for men with low or favorable intermediate risk prostate cancer. One group gets the standard five sessions, the other gets just two sessions. The goal is to see if the shorter course can maintain cancer control while better preserving sexual quality of life. 144 men will be followed for up to 5 years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stereotactic ablative body radiation (SABR)

What this could lead to

If successful, this could show that a shorter 2-session radiotherapy is as effective as the standard 5-session regimen, potentially reducing side effects and improving quality of life for men with prostate cancer.

What could go wrong

This is a phase 2 trial with only 144 participants, so results may not apply to all patients. The shorter course might not control the cancer as well or could have unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N3M5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••