Prostate cancer trial tests whether adding hormone therapy to radiation boosts success
NCT ID NCT01492972
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This phase 3 study is testing whether adding a short course of hormone therapy (androgen suppression) to image-guided radiation therapy helps men with intermediate-risk prostate cancer. About 192 men will receive either radiation alone or radiation plus hormone therapy. The goal is to see if the combination reduces the chance of cancer returning, while also tracking side effects and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Androgen suppression therapy (leuprolide, goserelin, buserelin, or triptorelin)
What this could lead to
If successful, this could show that adding short-term hormone therapy to radiation helps keep prostate cancer from coming back in men with intermediate-risk disease.
What could go wrong
This is an ongoing phase 3 trial, so results are not yet known. Hormone therapy can cause side effects like hot flashes, fatigue, and sexual problems, and it may not improve outcomes enough to justify those risks.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hampton University Proton Therapy Institute
RECRUITINGHampton, Virginia, 23666, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic
RECRUITINGScottsdale, Arizona, 85259-5499, United States
Contact Phone: •••-•••-••••
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Northwestern Medicine Chicago Proton Center
RECRUITINGWarrenville, Illinois, 60555, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oklahoma Proton Center
RECRUITINGOklahoma City, Oklahoma, 73142, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact