New hope for prostate cancer: drug combo before surgery shows promise
NCT ID NCT06627530
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving a combination of two hormone therapies (leuprorelin and darolutamide) for 24 weeks before prostate removal surgery can reduce or eliminate cancer more effectively than either drug alone. It involves 144 men with intermediate to high-risk prostate cancer. The main goal is to see if the combination leads to less cancer remaining in the surgical specimen.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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BP - A Beneficência Portuguesa de São Paulo
São Paulo, São Paulo, 01323001, Brazil
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Hospital Ophir Loyola
Belém, Pará, 66063-240, Brazil
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Hospital São Marcos
Teresina, Piauí, 64001-280, Brazil
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Hospital Universitário Pedro Ernesto
Rio de Janeiro, Rio de Janeiro, 20551-030, Brazil
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Hospital de Clínicas Ijuí
Ijuí, Rio Grande do Sul, 98700-000, Brazil
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Santa Casa de Misericórdia de Feira de Santana
Feira de Santana, Estado de Bahia, 44001-032, Brazil