Prostate cancer radiation showdown: which implant works best?

NCT ID NCT02960087

Ongoing Disease control Sponsor: Canadian Cancer Trials Group Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two types of brachytherapy (radiation implants) for localized prostate cancer: low-dose-rate (seed) implants and high-dose-rate (temporary) implants. About 334 men will receive one of the two treatments. Researchers will measure how well each controls cancer after 4 years and track side effects and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiation (brachytherapy implants)
What this could lead to: If successful, this could help doctors choose the best type of radiation implant for controlling localized prostate cancer with fewer side effects.
What could go wrong: This is a mid-stage trial, so results are not final. The dose for one arm was changed mid-study due to concerns about cancer returning, which adds uncertainty.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CARCINOMA

Contacts and locations

Locations

CHUM-Centre Hospitalier de l'Universite de Montreal

Montreal, Quebec, H2X 3E4, Canada
Hotel-Dieu de Quebec

Québec, Quebec, G1R 2J6, Canada
London Health Sciences Centre Research Inc.

London, Ontario, N6A 5W9, Canada
Odette Cancer Centre

Toronto, Ontario, M4N 3M5, Canada
Ottawa Hospital Research Institute

Ottawa, Ontario, K1H 8L6, Canada
The Jewish General Hospital

Montreal, Quebec, H3T 1E2, Canada
University Health Network

Toronto, Ontario, M5G 2M9, Canada

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