Which anesthetic keeps hearts steadier during ECT? new trial investigates

NCT ID NCT07273851

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two anesthetic drugs—propofol and a mix called ketofol—in 80 adults with major depression undergoing electroconvulsive therapy (ECT). The goal was to see which one keeps blood pressure and heart rate more stable during the procedure. Results could help doctors choose the safer option for ECT patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

propofol and ketofol (propofol plus ketamine)

What this could lead to

If ketofol works better, it could help doctors choose a safer anesthetic for ECT, reducing blood pressure drops during the procedure.

What could go wrong

This is a small, completed trial with only 80 participants, so results may not apply to everyone. The benefit is about short-term stability, not curing depression.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi, Pakistan

    Rawalpindi, Pakistan