Which anesthetic keeps hearts steadier during ECT? new trial investigates
NCT ID NCT07273851
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two anesthetic drugs—propofol and a mix called ketofol—in 80 adults with major depression undergoing electroconvulsive therapy (ECT). The goal was to see which one keeps blood pressure and heart rate more stable during the procedure. Results could help doctors choose the safer option for ECT patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- propofol and ketofol (propofol plus ketamine)
- What this could lead to
- If ketofol works better, it could help doctors choose a safer anesthetic for ECT, reducing blood pressure drops during the procedure.
- What could go wrong
- This is a small, completed trial with only 80 participants, so results may not apply to everyone. The benefit is about short-term stability, not curing depression.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi, Pakistan
Rawalpindi, Pakistan
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