Which sedative is safer for ICU intubation? new study investigates

NCT ID NCT06750939

Recruiting now Knowledge-focused Sponsor: Kocaeli City Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study observes 128 critically ill ICU patients to see how two common sedatives—propofol and ketamine—affect the risk of severe drops in blood pressure or cardiac arrest during emergency intubation. Propofol can lower blood pressure, while ketamine may help maintain stability. The goal is to provide clearer guidance for doctors choosing induction agents in high-risk situations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors choose safer drugs for emergency intubation in critically ill patients, potentially reducing life-threatening drops in blood pressure or cardiac arrest.
What could go wrong: This is an observational study, not a controlled trial, so it can show associations but not prove cause and effect. Results may not apply to all ICU settings or patient types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiac arrest cardiogenic shock Shock

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANAESTHETIC COMPLICATION CARDIAC CARDIOVASCULAR COLLAPSE INTUBATION COMPLICATION

Which sedative is safer for ICU intubation? new study investigates

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

Locations

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