New study tests if happiness skills can curb stimulant use in HIV patients

NCT ID NCT06814275

Recruiting now Symptom relief Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a 5-session online program teaching positive thinking skills can help people with HIV who use stimulants. Researchers want to see if it reduces stimulant use and depression by changing brain and immune function. 189 participants will be followed for 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Positive affect skills training (behavioral intervention)
What this could lead to: If it works, this could point toward a non-drug treatment to help people with HIV reduce stimulant use and improve mood.
What could go wrong: This is an early mechanistic study, not a large treatment trial. The intervention may not produce lasting changes, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

AIDS Depression depressive disorder HIV infectious disease substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION HUMAN IMMUNODEFICIENCY VIRUS (HIV) STIMULANT USE

Contacts and locations

Locations

Wake Forest University School of Medicine
RECRUITING

Winston-Salem, North Carolina, 27101, United States

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