New study tests if happiness skills can curb stimulant use in HIV patients

NCT ID NCT06814275

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a 5-session online program teaching positive thinking skills can help people with HIV who use stimulants. Researchers want to see if it reduces stimulant use and depression by changing brain and immune function. 189 participants will be followed for 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Positive affect skills training (behavioral intervention)

What this could lead to

If it works, this could point toward a non-drug treatment to help people with HIV reduce stimulant use and improve mood.

What could go wrong

This is an early mechanistic study, not a large treatment trial. The intervention may not produce lasting changes, and results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

AIDS Depression depressive disorder HIV infectious disease substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Wake Forest University School of Medicine

    RECRUITING

    Winston-Salem, North Carolina, 27101, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••