Brain fluid analysis may predict shunt success in elderly
NCT ID NCT04998175
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is investigating why some patients with normal pressure hydrocephalus (a condition that causes walking problems, memory loss, and incontinence) improve after a shunt surgery that drains extra fluid from the brain. Researchers will analyze proteins in the spinal fluid of 40 older adults before and after surgery, and compare them to healthy volunteers. The goal is to find biological markers that predict who will benefit from the procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ventriculoperitoneal shunt
What this could lead to
If successful, this research could help doctors predict which patients will benefit most from shunt surgery, improving treatment decisions.
What could go wrong
This is a small, early-stage observational study, not a treatment trial. It may not identify clear predictors or lead to immediate changes in care.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The second affliated hospital of zhejiang university
RECRUITINGHangzhou, Zhejiang, 310009, China
Contact Phone: •••-•••-•••• Email: •••••@•••••