Gut bacteria pills could help shed pounds, small study hints

NCT ID NCT04492605

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether two probiotic supplements, TCI378 and TCI507, can help adults lose weight and improve blood fats. 96 participants with a BMI of 24 or higher (or high body fat) take one capsule daily for two months. Researchers will measure changes in body fat, cholesterol, and other health markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Probiotics (TCI378 and TCI507)

What this could lead to

If successful, these probiotics could offer a safe, natural option to help with weight management and improve cholesterol levels.

What could go wrong

This is a small, early-stage trial with no blinding, so results may be influenced by placebo effects. Weight loss from probiotics is typically modest and not guaranteed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Taiwan University Hospital

    Taipei, Taiwan, 114, Taiwan

  • National Taiwan University Hospital

    Taipei, Taiwan