Could probiotics help restore bowel control after stoma surgery?

NCT ID NCT07369830

Recruiting now Disease control Sponsor: Huashan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether placing live probiotic tablets into the unused part of the gut during a temporary ileostomy can improve bowel function after the stoma is reversed. 156 adults with ultra-low rectal cancer who had sphincter-saving surgery will be randomly assigned to a low dose, high dose, or no probiotic. The main goal is to see if probiotics reduce symptoms like urgency, incontinence, and frequent bowel movements one month after reversal.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Clostridium butyricum (live) probiotic tablets
What this could lead to: If it works, this could offer a simple, low-cost way to improve bowel control and quality of life after stoma reversal surgery.
What could go wrong: This is an early-stage trial with no phase designation, so results are uncertain. The probiotic may not improve bowel function, and some people may experience bloating or discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RECTAL CANCER

Contacts and locations

Locations

Huashan Hospital Fudan University
RECRUITING

Shanghai, Shanghai Municipality, 200040, China

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