Probiotic pill may fight gum problems for people with braces

NCT ID NCT06752330

Completed Disease control Sponsor: University of Turin, Italy Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether taking a daily probiotic (Bifidobacterium Lactis HN019) can reduce plaque buildup and gum bleeding in people undergoing orthodontic treatment with braces or clear aligners. Sixty participants, aged 10 to 30, took the probiotic or a placebo for a period while researchers measured gum health. The goal was to see if this simple addition to oral hygiene could help prevent common dental issues during orthodontic care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Bifidobacterium Lactis HN019 probiotic (with Kluyveromyces Marxianus Fragilis B0399, colostrum, and biotin)
What this could lead to: If it works, this could point toward a simple way to improve gum health during orthodontic treatment.
What could go wrong: This is a small, completed trial with only 60 participants, so results may not apply to everyone. The effect on plaque and bleeding may be modest or not clinically significant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gingivitis periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DENTAL HYGIENE GINGIVITIS AND PERIODONTAL DISEASES ORTHODONTICS

Contacts and locations

Locations

AOU Città della Salute e della Scienza

Torino, Italy, 10126, Italy

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