Braces and bacteria: can we predict cavities during orthodontic treatment?

NCT ID NCT06824493

Recruiting now Knowledge-focused Sponsor: Xi'an Jiaotong University Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study follows 150 children and teens aged 8-18 who are getting braces to see how the treatment changes the bacteria in their mouths and the proteins in their saliva. Researchers will collect plaque and saliva samples before and during treatment to track these changes. The goal is to understand why some patients develop white spots or cavities while wearing braces, which could lead to better prevention strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help dentists predict and prevent cavities and white spots that often develop during orthodontic treatment.
What could go wrong: This is an observational study, so it cannot prove cause and effect. Results may not apply to all patients, and the findings are exploratory.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARIES, DENTAL ORTHODONTICS WHITE SPOT LESIONS [INITIAL CARIES] ON SMOOTH SURFACE OF TOOTH

Contacts and locations

Locations

tomatology Hospital of Xi'an Jiaotong University,
RECRUITING

Xi'an, Shaanxi, China

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