Genetic risk scores put to the test in heart health study

NCT ID NCT07087431

Recruiting now Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether telling people their genetic risk for coronary artery disease helps them lower cholesterol and improve heart health over one year. Researchers will enroll 500 adults aged 30-75 who are not on cholesterol medication. Half will get their genetic risk score right away, the other half after a year. The goal is to see if knowing this information leads to healthier behaviors and better heart outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If it works, this could show that sharing genetic risk information motivates people to improve their heart health, potentially leading to better prevention strategies.
What could go wrong: This is a behavioral study, not a drug trial, so the effect may be small or inconsistent. Results depend on participants' actions and may not apply to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atherosclerosis coronary artery disorder Genetic Risk Score

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE

Contacts and locations

Locations

Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

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