Can parathyroid surgery protect the heart and kidneys? new study follows 403 patients for 5 years

NCT ID NCT05469087

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study follows 403 adults with primary hyperparathyroidism who are having their overactive parathyroid gland removed. Researchers will track heart problems, cholesterol, blood sugar, artery stiffness, and quality of life for up to 5 years after surgery. The goal is to understand whether parathyroidectomy improves overall health beyond just fixing calcium levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could clarify whether parathyroidectomy improves long-term heart, kidney, and bone health in people with primary hyperparathyroidism.

What could go wrong

This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients, and benefits of surgery remain uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

primary hyperparathyroidism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nantes University Hospital

    RECRUITING

    Nantes, Loire-Atlantique, 44093, France