Scientists probe parathyroid tumors for clues to better surgery

NCT ID NCT05997810

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 study is collecting tumor samples from 839 people with hyperparathyroidism who are having parathyroid surgery. Researchers want to see if the genetic makeup of the tumors (whether they are monoclonal or polyclonal) relates to how many glands are affected and how well surgery works. The goal is to better understand the disease and possibly guide future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better predict which patients need more extensive surgery for hyperparathyroidism, leading to more personalized treatment.
What could go wrong
This is an observational biomarker study, not a treatment trial. It will not directly improve health outcomes, and results may not change current clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

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