Can a drug in the breathing tube stop Post-Surgery sore throat?

NCT ID NCT07202624

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether adding dexmedetomidine or alkalinized lidocaine to the breathing tube cuff could prevent sore throat after long surgery where patients lie face down. Only 4 adults having spine surgery took part. Researchers checked for sore throat, hoarseness, and cough in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
dexmedetomidine and alkalinized lidocaine
What this could lead to
If it works, this could point toward a simple way to reduce sore throat after surgery, improving patient comfort.
What could go wrong
This is a very small, early-phase trial with only 4 participants, so results may not apply to larger groups. The drugs may not work better than standard care.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Prince Sultan Military Medical City

    Riyadh, 12232, Saudi Arabia

More trials for these conditions

Other studies related to the condition(s) this trial covers.