Massive new study aims to stop Post-Surgery confusion in seniors

NCT ID NCT04355195

Recruiting now Prevention Sponsor: Charite University, Berlin, Germany Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 2 times

Summary

This study tests a structured care program to prevent postoperative delirium (sudden confusion) in patients aged 70 and older undergoing surgery. Over 18,000 participants will receive evidence-based prevention measures, with electronic tracking to ensure consistency. Additional sub-studies explore how blood pressure changes and brain wave monitoring might predict delirium risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: structured care program (evidence-based prevention measures, electronic documentation, and monitoring devices)
What this could lead to: If successful, this could establish a practical, hospital-wide approach to reduce postoperative delirium in older patients, improving recovery and quality of life.
What could go wrong: This is an implementation study, not a drug trial, so benefits depend on hospital staff following the program consistently. The sub-studies are exploratory and may not yield clear results.

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Conditions

The condition(s) this trial relates to.

delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DELIRIUM IN OLD AGE

Contacts and locations

Locations

Department of Anesthesiology and Intensive Care Medicine (CBF), Charité - Universitätsmedizin Berlin
RECRUITING

Berlin, 12203, Germany
Department of Anesthesiology and Intensive Care Medicine (CCM/CVK) Berlin, Carité - Universitätsmedizin Berlin
RECRUITING

Berlin, 13353, Germany

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