Drug-Only approach may prevent Post-Procedure pancreatitis without stent risks
NCT ID NCT07117318
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ways to prevent pancreatitis after a procedure called ERCP: giving a rectal anti-inflammatory drug (NSAID) alone versus the drug plus placing a small tube (stent) in the pancreas. The trial enrolls about 1,278 high-risk patients aged 18-90 who have not had prior pancreatic stenting. The goal is to see if the drug alone works just as well, avoiding the extra complexity and risks of stent placement.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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986 Hospital of Xijing Hospital
RECRUITINGXi'an, Shaanxi, 710000, China
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Affiliated Hangzhou First People's Hospital
NOT_YET_RECRUITINGHangzhou, Zhejiang, 310000, China
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Department of Endoscopy, Eastern Hepatobiliary Hospital, Second Military Medical University
RECRUITINGShanghai, Shanghai Municipality, 201823, China
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Department of Gastroenterology, Fujian Medical University Xiamen Humanity Hospital
RECRUITINGXiamen, Fujian, 361000, China
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Department of Gastroenterology, Huaihe Hospital of Henan University
RECRUITINGKaifeng, Henan, 475000, China
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Department of Gastroenterology, The 960th Hospital of the PLA
RECRUITINGJinan, Shandong, 250000, China
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Department of gastroenterology, Second Affiliated Hospital of Chongqing Medical University
RECRUITINGChongqing, Chongqing Municipality, 400010, China
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Harbin Medical University Affiliated Fourth Hospital
RECRUITINGHarbin, Heilongjiang, 150000, China
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Shandong Provincial Third Hospital
NOT_YET_RECRUITINGJinan, Shandong, 250000, China
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The Second Affiliated Hospital of Harbin Medical University
RECRUITINGHarbin, Heilongjiang, 150000, China
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The Third Xiangya Hospital of Central South University
NOT_YET_RECRUITINGChangsha, Hunan, 410000, China
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The first medical center, Chinese PLA General Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100000, China
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Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, 430000, China
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Xijing of Digestive Diseases
RECRUITINGXi'an, Shaanxi, China
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the First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Common painkiller may prevent pancreatitis after bile duct procedure
- Simple IV drip may prevent painful complication after common bile duct procedure
- Which drug best prevents pancreatitis in kids after ERCP?
- Less acidic dye may reduce pancreatitis risk after common procedure
- Could a simple pill prevent a painful complication after endoscopy?
- Can a simple tool reduce pancreatitis risk during ERCP?