Less acidic dye may reduce pancreatitis risk after common procedure

NCT ID NCT07391787

Completed Disease control Sponsor: Shandong University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether using low-acid contrast media (dye) during ERCP can lower the chance of developing pancreatitis afterward. Researchers reviewed records of nearly 4,000 patients from five hospitals. They compared patients who received low-acid contrast media to those who received standard contrast media. The goal is to find a safer option for this common procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ioversol, Iohexol (low-acid contrast media)
What this could lead to: If low-acid contrast media works, it could offer a simple way to lower the risk of pancreatitis after ERCP, making the procedure safer.
What could go wrong: This is a retrospective study, not a controlled trial, so results may be influenced by other factors. The benefit may be small or not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute pancreatitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-ERCP ACUTE PANCREATITIS

Contacts and locations

Locations

Department of Gastroenterology, Qilu Hospital, Shandong University

Jinan, Shandong, 250012, China
Qilu hospital, Shandong University

Jinan, Shandong, China

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