Which drug best prevents pancreatitis in kids after ERCP?
NCT ID NCT05664074
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 192 children having an ERCP procedure to see which drug—rectal indomethacin or IV ketorolac—better prevents post-ERCP pancreatitis. Both are anti-inflammatory medicines given before the procedure. The goal is to find the most effective option for kids.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- rectal indomethacin and intravenous ketorolac
- What this could lead to
- If this trial shows one drug is better, it could help doctors choose the best way to prevent pancreatitis after ERCP in children.
- What could go wrong
- This is a completed Phase 4 trial with 192 children, but results may not apply to all patients. Both drugs have known side effects like bleeding risk.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a simple tool reduce pancreatitis risk during ERCP?