Could a simple pill prevent a painful complication after endoscopy?

NCT ID NCT05252754

First seen Jan 11, 2026

Summary

This study tests whether adding an oral medication (tacrolimus) before an ERCP procedure can prevent pancreatitis, a painful inflammation of the pancreas that sometimes occurs afterward. About 4,800 adults undergoing ERCP will be randomly assigned to receive either the standard rectal medication alone or the standard medication plus oral tacrolimus. The goal is to see if the combination reduces the number of people who develop pancreatitis after the procedure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Apollo Multispecialty Hospitals,

    NOT_YET_RECRUITING

    Kolkata, West Bengal, 700054, India

    Contact Email: •••••@•••••

  • Asian Institute of Gastroenterology

    RECRUITING

    Hyderabad, Andhra Pradesh, 500082, India

    Contact Email: •••••@•••••

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Post Graduate Institute of Medical Education and Research

    NOT_YET_RECRUITING

    Chandigarh, 160012, India

    Contact Email: •••••@•••••

  • Singapore General Hospital

    NOT_YET_RECRUITING

    Singapore, 169608, Singapore

    Contact Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

acute pancreatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.