Simple drug during surgery may stop chronic pain in breast cancer patients
NCT ID NCT04874038
First seen Nov 17, 2025 · Last updated May 13, 2026 · Updated 21 times
Summary
This study tests whether giving the numbing drug lidocaine through a vein during breast cancer surgery can prevent persistent pain that often lasts for months after the operation. About 1,600 adults having a lumpectomy or mastectomy will be randomly assigned to receive either lidocaine or a placebo during surgery. The main goal is to see if fewer people in the lidocaine group develop pain 3 months after surgery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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B.P. Koirala Institute of Health Sciences
RECRUITINGDharān, Nepal
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Eastern Health- Health Sciences Centre
RECRUITINGSt. John's, Newfoundland and Labrador, Canada
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Foothills Medical Centre
RECRUITINGCalgary, Alberta, Canada
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Humber River Hospital
RECRUITINGToronto, Ontario, Canada
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Hôpital Maisonneuve-Rosemont
RECRUITINGMontreal, Quebec, Canada
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IWK
RECRUITINGHalifax, Nova Scotia, Canada
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Juravinski Hospital
RECRUITINGHamilton, Ontario, Canada
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Mount Sinai Hospital
RECRUITINGToronto, Ontario, Canada
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North York General Hospital
RECRUITINGNorth York, Ontario, Canada
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Obafemi Awolowo University Teaching Hospitals Complex
RECRUITINGIle-Ife, Nigeria
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St. Michael's Hospital
RECRUITINGToronto, Ontario, Canada
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Sturgeon Community Hospital
RECRUITINGEdmonton, Alberta, Canada
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Sunnybrook Health Sciences Centre
RECRUITINGToronto, Ontario, Canada
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The Ottawa Hospital
RECRUITINGOttawa, Ontario, Canada
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Thunder Bay Regional Health Sciences Centre
RECRUITINGThunder Bay, Ontario, Canada
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University Health Network
RECRUITINGToronto, Ontario, Canada
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Women's College Hospital
RECRUITINGToronto, Ontario, Canada
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Conditions
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