Breakthrough drug combo may stop hepatitis c spread in organ transplants

NCT ID NCT04508907

First seen Dec 30, 2025 · Last updated May 10, 2026 · Updated 22 times

Summary

This study tests whether a short course of two drugs (glecaprevir/pibrentasvir and ezetimibe) can prevent hepatitis C infection in people who receive a kidney, heart, lung, or pancreas from a hepatitis C-positive donor. About 200 participants who are hepatitis C-negative and awaiting a transplant will take the drugs right after surgery. The goal is to see if this approach stops the virus from taking hold, while keeping the organ and patient healthy for at least a year.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEPATITIS C are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Mayo Clinic in Arizona

    Phoenix, Arizona, 85054, United States

Conditions

Explore the condition pages connected to this study.