New drug combo may stop hepatitis c spread in organ transplants

NCT ID NCT04508907

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a short course of two drugs (glecaprevir/pibrentasvir and ezetimibe) can prevent hepatitis C infection in people who receive a kidney, heart, lung, or pancreas from a donor with hepatitis C. About 200 participants who are hepatitis C-negative will take the drugs soon after transplant. The goal is to see if this approach stops the virus from taking hold and improves survival of both the patient and the transplanted organ.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Arizona

    Phoenix, Arizona, 85054, United States

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