Can school programs curb teen drug use? cherokee nation trial seeks answers

NCT ID NCT04839978

Completed Prevention Sponsor: Emory University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed trial tested two school-based programs—Connect and CMCA—to prevent drug and alcohol misuse among 10th graders in rural Cherokee Nation high schools. Over 900 students from 20 schools participated, with some schools receiving the programs and others serving as controls. The study tracked alcohol, marijuana, and opioid use over time to see if the programs made a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: school-based screening, brief intervention, and referral program
What this could lead to: If effective, this approach could reduce drug and alcohol misuse in rural Native American communities.
What could go wrong: The trial is completed but results are not yet widely known. The programs may not work for all teens or in other settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

opiate dependence opioid abuse prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID ABUSE

Contacts and locations

Locations

Cherokee Nation Reservation

Tahlequah, Oklahoma, 74464, United States

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