Can school programs curb teen drug use? cherokee nation trial seeks answers

NCT ID NCT04839978

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed trial tested two school-based programs—Connect and CMCA—to prevent drug and alcohol misuse among 10th graders in rural Cherokee Nation high schools. Over 900 students from 20 schools participated, with some schools receiving the programs and others serving as controls. The study tracked alcohol, marijuana, and opioid use over time to see if the programs made a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

school-based screening, brief intervention, and referral program

What this could lead to

If effective, this approach could reduce drug and alcohol misuse in rural Native American communities.

What could go wrong

The trial is completed but results are not yet widely known. The programs may not work for all teens or in other settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

opiate dependence opioid abuse prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cherokee Nation Reservation

    Tahlequah, Oklahoma, 74464, United States