Can dropping pounds before hernia surgery boost outcomes?
NCT ID NCT05925959
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a weight loss program before complex hernia repair helps patients feel better a year later compared to having surgery right away. About 258 obese adults with large hernias will either join a weight management plan with diet, exercise, and medication, or go straight to surgery. The main goal is to see if upfront surgery is just as good for quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Preoperative Weight Management Program (lifestyle changes and anti-obesity medication)
What this could lead to
If successful, this could show that losing weight before hernia repair improves long-term quality of life and reduces complications.
What could go wrong
This is a mid-stage trial with 258 participants, so results may not apply to all patients. Weight loss programs can be hard to stick with, and some people may not lose enough weight to make a difference.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic Main Campus
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••