Can dropping pounds before hernia surgery boost outcomes?

NCT ID NCT05925959

Recruiting now Disease control Sponsor: Benjamin T. Miller Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a weight loss program before complex hernia repair helps patients feel better a year later compared to having surgery right away. About 258 obese adults with large hernias will either join a weight management plan with diet, exercise, and medication, or go straight to surgery. The main goal is to see if upfront surgery is just as good for quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Preoperative Weight Management Program (lifestyle changes and anti-obesity medication)
What this could lead to: If successful, this could show that losing weight before hernia repair improves long-term quality of life and reduces complications.
What could go wrong: This is a mid-stage trial with 258 participants, so results may not apply to all patients. Weight loss programs can be hard to stick with, and some people may not lose enough weight to make a difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hernia, Abdominal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABDOMINAL WALL HERNIA

Contacts and locations

Locations

Cleveland Clinic Main Campus
RECRUITING

Cleveland, Ohio, 44195, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

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