Belly wall transplants: a new frontier in organ transplants?

NCT ID NCT03310905

Recruiting now Disease control Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests if transplanting a piece of abdominal wall (the muscle and tissue covering the belly) can safely repair large defects, like hernias or injuries. It can be done alone or with another organ transplant, like a kidney or liver. Only 5 adults aged 18-65 are being enrolled to see if the transplant stays healthy after 18 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Abdominal wall transplant (a surgical procedure)
What this could lead to: If successful, this could offer a new way to repair large abdominal wall defects in people who also need an organ transplant, potentially improving surgical outcomes.
What could go wrong: This is a very early, tiny trial with only 5 participants. The procedure is complex and carries risks like rejection, infection, and need for lifelong immune-suppressing drugs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

abdominal wall malformation chronic intestinal failure Hernia Hernia, Abdominal kidney failure liver failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABDOMINAL WALL DEFECT ABDOMINAL WALL FISTULA ABDOMINAL WALL HERNIA ABDOMINAL WALL INJURY TRANSPLANT; FAILURE, BOWEL TRANSPLANT; FAILURE, LIVER TRANSPLANT;FAILURE,KIDNEY

Contacts and locations

Locations

Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States

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