Nose spray showdown: which sedative works best for anxious children?
NCT ID NCT07180095
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests two different nose sprays—dexmedetomidine and ketamine—to see which one better calms children aged 2 to 6 before surgery. Sixty kids will receive one of the two sprays, and researchers will measure how sleepy they get and how easily they separate from their parents. The goal is to find a safer, more effective way to reduce preoperative anxiety in young patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intranasal dexmedetomidine and intranasal ketamine
What this could lead to
If it works, this could point toward a better way to calm children before surgery, reducing anxiety and making separation from parents easier.
What could go wrong
This is a small, early-phase trial with only 60 children, so results may not apply to all kids. Both drugs can cause side effects like low blood pressure or slow heart rate.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.