Personalized blood clot prevention for pregnant women put to the test

NCT ID NCT03659708

Recruiting now Prevention Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special scoring tool (the Lyon-VTE score) can better prevent dangerous blood clots in pregnant women at high risk compared to standard care. About 600 pregnant women with a personal history of blood clots or a clotting disorder will be randomly assigned to either score-guided prevention or usual recommendations. The goal is to see if personalized care is safer, more effective, and more cost-efficient.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Lyon-VTE score (risk assessment tool)
What this could lead to: If successful, this could provide a validated, personalized approach to prevent dangerous blood clots during pregnancy, reducing unnecessary treatment and costs.
What could go wrong: This is a relatively early-stage trial (phase not specified) and the score has only been tested in retrospective and small prospective studies. It may not prove more effective or cost-saving than current care.

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Conditions

The condition(s) this trial relates to.

Thromboembolism venous thromboembolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PREGNANCY THROMBOEMBOLISM

Contacts and locations

Locations

Hôpital Cardiologique L. Pradel
RECRUITING

Bron, 69677, France

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