Could a common pain pill protect the brain during surgery?
NCT ID NCT07630753
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving pregabalin before brain tumor surgery can safely reduce pressure inside the skull. One hundred adults will receive either pregabalin or a placebo before and on the morning of surgery. Researchers will measure pressure using a painless eye ultrasound instead of an invasive brain monitor.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pregabalin
- What this could lead to
- If it works, this could offer a simple, non-invasive way to manage brain pressure during surgery and speed up recovery.
- What could go wrong
- This is a small, early-phase study using an indirect pressure measurement. The drug may not reduce pressure meaningfully, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Benha University Hospital
Banhā, Qalyubia Governorate, 13511, Egypt
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