App aims to stop depression before it starts: 9,000-person trial launched

NCT ID NCT06351800

Not yet recruiting Prevention Sponsor: The Mediterranean Institute for the Advance of Biotechnology and Health Research Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a personalized smartphone app can prevent depression and anxiety in adults who do not currently have these conditions. Over 9,000 participants in Spain will use the app, which creates a custom plan with activities like exercise, sleep improvement, and problem-solving. The trial will track how many people develop depression or anxiety over a year, comparing the app group to a control group receiving self-help booklets.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: personalized app-based prevention program
What this could lead to: If successful, this could provide an effective, scalable way to prevent depression and anxiety in the general population using a smartphone app.
What could go wrong: This is a prevention trial, not a treatment. The intervention is self-guided and relies on participants' engagement, which may vary. Results may not apply outside Spain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Depression anxiety disorder prevention target depressive disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY DISORDERS DEPRESSION

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Other studies related to the condition(s) this trial covers.